Assessment discovered that conolidine and cannabidiol substantially blocked Cav2.2 channels. During the peripheral and central nervous system, Cav2.2 channels are located predominantly at presynaptic terminals32 and Perform necessary roles in discomfort perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds that have an impact on presynaptic Cav2.2 ... https://hayleyo666hyk7.wikigop.com/user