When specified concomitantly with promethazine, the dose of barbiturates need to be decreased by at least one-half, plus the dose of narcotics needs to be minimized by a person-quarter to at least one-50 %. Dosage must be individualized. Excessive quantities of promethazine HCl relative to the narcotic might cause restlessness https://wockusa.com/product/nanozora-ozoralizumab/