In an effort to rationalise the observed ABL kinase inhibitory success from a 3D structural point of view, the direct compounds I and II, along with the recently intended derivatives 4a, 4b, and 5 were docked in the catalytic kinase domains of BCR-ABLWT (PDB code: 3OXZ) and BCR-ABLT315I (PDB code: https://fernandobthvk.arwebo.com/53995207/indazole-no-further-a-mystery