Buffalo Museum of Science map). Generally, it opens at 10 AM and shuts at 5 PM, but weekend breaks may have prolonged hours Exist Any Type Of Admission Discount Rates Offered? Yes, you can find admission discount rates at the museum. Appreciate your browse through! Is the Museum Wheelchair Accessible? https://codyryeih.thezenweb.com/enjoy-innovative-displays-and-innovations-at-the-buffalo-museum-of-science-73131353