Pentobarbital will decrease the level or effect of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. When barbiturates like Nembutal are abused, they are not usually the primary drug of abuse. Like https://top10bookmark.com/story20167943/indicatori-sulla-pentobarbital-si-deve-sapere